Serums

A small step in your routine with high-performance results. Synergie Skin’s evidence-based face serums are formulated with concentrated active ingredients designed to support a wide range of skin concerns, including dehydration, visible redness, uneven skin tone, environmental stress and blemish-prone skin.

From topical vitamin serums and hydration boosters to targeted brightening and pro-ageing formulas, each serum is developed to support healthier, stronger and more radiant-looking skin. Originally created for the professional clinic market, these advanced formulas combine visible results with Synergie Skin’s Clean Science® philosophy.

A small step in your routine with high-performance results. Synergie Skin’s evidence-based face serums are formulated with concentrated active...Read more

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12 products • Serums

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Vitamin B
BEST SELLER
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Vitamin B

Award-winning 13% niacinamide serum to strengthen skin

$130 - 30mL
SuperSerum+
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SuperSerum+

Youth renew serum with six age-defying actives

$176 - 30mL
Effica C
Effica C
BEST SELLER
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Effica C

Essential vitamin C serum with stabilised L-ascorbic acid

$130 - 30mL
HyalaVive
HyalaVive
BEST SELLER

HyalaVive

Hydration and barrier support serum with triple hyaluronic acid and vitamin B12

$145 - 30mL
PressPause
PressPause
NEW

PressPause

Skin support through perimenopause and menopause

$155 - 30mL
XCell B
XCell B
BEST SELLER

XCell B

Accelerated 21% niacinamide serum to refine skin clarity

$145 - 30mL
Ultimate A
Ultimate A
BEST SELLER

Ultimate A

Encapsulated retinol serum to regulate skin renewal

$145 - 30mL
Acceler-A
Acceler-A

Acceler-A

Retinoid serum to firm, smooth, and refine uneven tone

$155 - 30mL
EnLighten
EnLighten

EnLighten

Brightening serum to fade and balance uneven skin tone

$155 - 30mL
RetiFol
RetiFol

RetiFol

0.4% encapsulated retinol plus peptides for skin renewal

$150 - 30mL
Blem-X
Blem-X

Blem-X

Targeted spot treatment

$72 - 15mL
AlgiZome
AlgiZome

AlgiZome

Pro-ageing exosome skin booster

$120 - 30mL

The SynThesis Journal

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Which Synergie Skin Vitamin B3 Serum Is Right For You?

Which Synergie Skin Vitamin B3 Serum Is Right For You?

This guide breaks down the difference between Synergie Skin's three vitamin B3 serums: Vitamin B, XCell-B, and Priority B, so you can find your perfect match.

Read the full article
Moisturisers Vs Serums

Moisturisers Vs Serums

Over the past few years, serums have risen to take the place of toners to become the new essential in your twice-daily skincare routine. But with such a wide range of serums, all varying in quality, which one should you choose and exactly what are they designed to achieve?!
Read the full article
The Age Defying Skincare Routine a Qualified Skin Scientist Follows

The Age Defying Skincare Routine a Qualified Skin Scientist Follows

On her path to ageing gracefully, cosmetic chemist Terri (Vinson) Jones shares her personal routine.

Read the full article
Which Synergie Skin Vitamin B3 Serum Is Right For You?

Which Synergie Skin Vitamin B3 Serum Is Right For You?

This guide breaks down the difference between Synergie Skin's three vitamin B3 serums: Vitamin B, XCell-B, and Priority B, so you can find your perfect match.

Read the full article
Moisturisers Vs Serums

Moisturisers Vs Serums

Over the past few years, serums have risen to take the place of toners to become the new essential in your twice-daily skincare routine. But with such a wide range of serums, all varying in quality, which one should you choose and exactly what are they designed to achieve?!
Read the full article
The Age Defying Skincare Routine a Qualified Skin Scientist Follows

The Age Defying Skincare Routine a Qualified Skin Scientist Follows

On her path to ageing gracefully, cosmetic chemist Terri (Vinson) Jones shares her personal routine.

Read the full article
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Synergie Face Serums: A Deep Dive into Concentrated Efficacy

All Synergie Skin products are formulated with evidence-based actives at optimal doses, backed by clinical research and chosen for real, visible results. Each serum is crafted with Clean Science® principles, supporting healthier, revitalised skin. Our range of hydrating serums targets a spectrum of skin challenges, from sensitivity and hyperpigmentation to the visible signs of ageing, aligning seamlessly with your skin's unique characteristics and needs.


What Is a Facial Serum?

A serum is a highly concentrated product that delivers active ingredients deep into the skin. Unlike moisturisers, which primarily hydrate and protect the skin’s surface, serums for the face target particular concerns such as fine lines, uneven tone, dehydration or dullness.
 

In essence, a face serum acts as the treatment step in your skincare routine. It enhances results and supports overall skin health with precision and efficacy.


Shop the Best Serums for Your Skin at Synergie Skin

Elevate your daily skincare routine with Synergie Skin’s evidence-based formulations. Beyond serums, we also offer expertly formulated cleansers to prepare the skin, exfoliants to target texture and moisturisers to support hydration and balance. Complement your regimen with calming facial oils, revitalising masks and complexion-enhancing foundations.


Order online and begin your journey towards clearer and healthier-looking skin.


FAQs

Start by understanding what your skin really needs, then look for ingredients that target those concerns. If your goal is to maintain your skin’s barrier, a vitamin B serum is a great option as it supports the skin’s natural lipid balance, including the production of ceramides, which play an important role in maintaining a healthy-looking skin barrier. For dull skin or those wanting to address uneven skin tone, reach for a vitamin C serum to brighten and protect against daily environmental stress. And if you’re looking to smooth the appearance of fine lines or address your skin’s texture, a retinol serum can help boost renewal and reveal more youthful-looking skin over time.

Most serums are suitable for daily use, in the morning and evening. Brightening serums such as vitamin C are best used in the morning, while rejuvenating formulas like retinol are usually reserved for evening use to support overnight renewal. Always follow the specific usage directions on your chosen Synergie Skin serum, and introduce new actives gradually so your skin has time to adjust.

As a general guide, apply your serum after cleansing and before moisturising to allow the active ingredients to penetrate effectively. Follow the directions of use for each differing serum, however.

It depends on the formulation. Always check the recommendations associated with that particular serum, and if you’ve decided to go ahead and try it, it’s best to patch test first. For example, if you’re trying a new anti-ageing serum for the first time, apply a small amount behind your ear or on the inside of your arm, and leave it for 24 to 48 hours. During this time, watch for any signs of redness, itching or irritation. If your skin remains calm, it’s a good indication that the product is suitable for use on your face. If you have any hesitations, it’s always best to speak to a professional who can help guide you to the most suitable formulation for your concern.

It varies from person to person, but most people notice a visible difference after four to six weeks of regular use. This allows active ingredients to build up in the skin and help maintain visible improvements over time. Think of it as long-term care rather than a quick fix. The more consistent you are, the better your results will be.