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  • 6% advanced vitamin A RetiGen Complex™

  • Regulates cell turnover for smoother, brighter skin

  • Reduces fine lines and wrinkles by promoting collagen

  • Controls oil, blemishes and acne breakouts

  • For optimal penetration, use with Synergie Skin Home Roller


An active, non-irritating and stable vitamin A serum containing the hero retinoid, hydroxypinacolone retinoate (HPR) as the key ingre...

An active, non-irritating and stable vitamin A serum containing the hero retinoid, hydroxypinacolone retinoate (HPR) as the key ingredient of our trademarked blend. This evening serum promotes healthy skin renewal, reverses visible signs of ageing, and clarifies pores for smoother, clearer and brighter skin.

Synergie Skin's Vitamin A suite also includes the following formulations:

 Ultimate A (Stabilised Retinol, moderate potency, low Irritation profile). This is the recommended Vitamin A serum for new users and those with sensitive skin. 

 RetiFol (Encapsulated Retinol, moderate potency, low Irritation profile).  All skin types except sensitive. First-time Vitamin A clients should start with Ultimate A before advancing to RetiFol after 3-6 months, monitoring tolerance.

• Acceler-A (Hydroxy-pinacolone retinoate, high potency, moderate irritation profile).

 A+  Hydroxy-pinacolone retinoate, high potency, high potency, moderate irritation profile). This product is not available online and is exclusively prescribed by Synergie Practitioners. 

Recommended for

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• Fine lines and wrinkles

• Hyperpigmentation

• Redness

• Sun damage

• Acne and breakouts

Good to know

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• Vegan

• Nut free

• Gluten free

• Australian made

• pH 6.5 - 7.5

Key ingredients

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6% RetiGen Complex (Reti from retinoid and 'Gen' as in to 'generate' new cells) is our proprietary retinoid blend. A powerful blend of skin perfecting ingredients with the cutting-edge hero retinoid, hydroxypinacolone retinoate, at the centre.

Hydroxypinacolone retinoate (HPR)
This next generation vitamin A ingredient requires no metabolic conversion by the target cell in order to exert its numerous beneficial effects. It is the fastest acting and most potent form of vitamin A, next only to prescription retinoic acid. Clinical studies demonstrates that HPR visibly reduces the appearance of lines and wrinkles in as little as 14 days while also brightening uneven skin tone, clearing, firming and plumping the skin, reducing visible pores and normalising excess oil production.

Coenzyme Q10
Found in every cell and tissue within the human body, Coenzyme Q10 is involved in numerous biological functions including energy production and stablising free radicals. Its levels decrease with age, resulting in a reduced ability to produce collagen and elastin. Topically applied, this ingredient assists in reversing and preventing the visible signs of ageing.

Green tea
A potent antioxidant that neutralises free radicals and prevents oxidative stress. Green tea is rich in polyphenols and epigallocatechin gallate (EGCG: the most abundant type of catechin, a plat micronutrient packed with natural antioxidants), which inhibit elastase and MMPs, responsible for the breakdown of collagen and elastin. Green tea also inhibits the production of tyrosinase, one of the key enzymes involved in pigment production, thereby resulting in a birghter and more even complexion.

Additional ingredients
This formula contains dimethyl isosorbide (DMI) to enahnce the delivery of active ingredients into the skin.

A note from Terri

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HPR is the most bioavailable and potent form of non-prescription Vitamin A currently on the market. Clinical studies demonstrate that HPR visibly reduces the appearance of fine lines within 14 days while also addressing uneven skin tone, reducing acne breakouts, regulating new cell production, and normalising oil flow.

Full ingredient list

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Aqua (Purified Australian Rain Water), Glycerin, Isoamyl Laurate, Dimethyl Isosorbide, Methylpropanediol, Caprylyl Glycol, Tocopherol (Vitamin E), Acrylates/C10-30 Alkylacrylate Crosspolymer, Hydroxypinacolone Retinoate, Camellia Sinensis (Green Tea) Leaf Extract, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Oil, Ubiquinone, Phenylpropanol, Sodium Phytate, 1,2-Hexanediol, Hydroxyacetophenone, Alcohol (Grain Derived), Sodium Hydroxide, d-Limonene, Linalool.

As part of our commitment to innovation, Synergie formulations are updated from time to time. Always refer to the ingredient list on the box for the most current version.


Apply one pump over the face and neck.

How to gradually phase in a new vitamin A serum:
First-time Vitamin A users should start by using Ultimate A or RetiFol, then advance to Acceler-A after 3-6 months, monitoring tolerance. Those with sensitive skin may wish to remain on Ultimate A as the vitamin A product of choice.
Weeks 1 and 2: Apply new retinoid serum every 3rd night, alternating with less potent retinoid serum (if applicable)
Weeks 3 and 4: Apply new retinoid serum every 2nd night, alternating with less potent retinoid serum (if applicable)
From Week 5: Apply new retinoid serum every night

*Not suitable for individuals who are pregnant or lactating

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