Where to buy


  • 6% vitamin A complex with added folic acid

  • Regulates cell turnover for smooth, bright skin

  • Reduces fine lines and wrinkles by promoting collagen

  • Controls oil and acne breakouts

  • Reduces the appearance of hyperpigmentation and uneven skin tone

  • Use with Rejuvaderm Home Roller for optimal penetration


An advanced vitamin A serum with the hero retinoid, hydroxypinacolone retinoate (HPR), and folic acid. This evening serum promotes he...

An advanced vitamin A serum with the hero retinoid, hydroxypinacolone retinoate (HPR), and folic acid. This evening serum promotes healthy skin renewal, reverses visible signs of ageing and clarifies pores for smoother, clearer and brighter skin.

This product is exclusive to Synergie Practitioner clinics.

Synergie Skin's Vitamin A suite also includes the following formulations:

Ultimate A (Stabilised Retinol, moderate potency, low Irritation profile). This is the recommended Vitamin A serum for new users and those with sensitive skin. 

 RetiFol (Encapsulated Retinol, moderate potency, low Irritation profile).  All skin types except sensitive. First-time Vitamin A clients should start with Ultimate A before advancing to RetiFol after 3-6 months, monitoring tolerance.

Acceler-A (Hydroxy-pinacolone retinoate, high potency, moderate irritation profile).

 A+  Hydroxy-pinacolone retinoate, high potency, high potency, moderate irritation profile). This product is not available online and is exclusively prescribed by Synergie Practitioners.  

Key Ingredients

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6% RetiGen Complex™ (Hydroxypinacolone retinoate, green tea, coenzyme 010) Proprietary retinoid blend: A powerful blend of skin perfecting ingredients with the cutting-edge hero retinoid, hydroxypinacolone retinoate, at the centre.

Hydroxypinacolone retinoate: This next generation vitamin A ingredient requires no metabolic conversion by the target cell in order to exert its numerous beneficial effects. Clinical studies demonstrate that hydroxypinacolone retinoate visibly reduces the appearance of lines and wrinkles in as little as 14 days, while also brightening clearing, firming and plumping the skin, reducing visible pores and normalising excess oil production.    

Coenzyme Q10: Involved in numerous biological functions, including energy production and stabilising free radicals. Coenzyme 010 levels decrease with age resulting in a reduced ability to produce collagen and elastin. Topically applied, this ingredient assists in reversing and preventing the visible signs of ageing.

Green tea: A potent antioxidant that neutralises free radicals and prevents oxidative stress. Green tea is rich in polyphenols and epigallocatechin gallate, which inhibit elastase and matrix metalloproteinases (MMPs), responsible for the breakdown collagen and elastin. Green tea also inhibits the production of tyrosinase, a key enzyme involved in pigment production, thereby resulting in a brighter and more even complexion.

Folic acid: Proven skin regeneration properties and can modulate and increase the rate of DNA repair in UV-damaged skin. Studies demonstrate folic acid's ability to revitalise fibroblast cells, which are responsible hyaluronic acid, collagen and elastin production. Folic acid also increases the skin's moisturisation and decreases transepidermal water loss (TEWL) without any significant change of sebum secretion.

Additional ingredients: Dimethyl isosorbide

A note from Terri

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HPR (Hydroxy Pinacolone Retinoate) is the most active and potent form of Vitamin A on the market right now, next only to prescription retinoids. Clinical studies demonstrate that HPR visibly reduces the appearance of fine lines and wrinkles in 14 days while also brightening, reducing acne breakouts, and normalising excess oil production. This ingredient truly is the new queen of Vitamin A.

Full Ingredient List

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Aqua (Purified Australian Rain Water), Glycerin, Dimethyl Isosorbide, Isoamyl Laurate, Methylpropanediol, Caprylyl Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopherol (Vitamin E), Hydroxypinacolone Retinoate, Folic Acid, Camellia Sinensis (Green Tea) Leaf Extract, Helianthus Annuus (Sunflower) Seed Oil, Cymbopogon Martini (Palmarosa) Oil, Ubiquinone, Phenylpropanol, Sodium Phytate, 1,2-Hexanediol, Hydroxyacetophenone, Alcohol (Grain Derived), Sodium Hydroxide, d-Limonene, Geraniol, Linalool.

As part of our commitment to innovation, Synergie formulations are updated from time to time. Always refer to the ingredient list on the box for the most current version.


Apply one pump over face and neck. Always apply sparingly and monitor tolerance.

Always apply A+ sparingly and monitor tolerance. Start by using Ultimate A and  advance to A+ after 3 to 6 months, alternating every evening over a 4 week period to gradually acclimatise to A+. 

Not recommended for individuals who are pregnant or lactating.

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